| Reaction |
- (R)-BINAP or (R)-Tol-BINAP can be combined with dichloro(1,5-cyclooctadiene)ruthenium to form precursors to NOYORI CATALYST SYSTEMS. These systems exhibit very high catalytic activity and enantioselectivity in the hydrogenation of a wide range of substrates. NOYORI CATALYST SYSTEMS have been shown to effect highly enantioselective hydrogenation of functionalized ketones where the substituents are dialkylamino, hydroxy, siloxy, carbonyl, ester, amide or thioester.
- Useful ligand in asymmetric Heck processes.
- Ligand employed in palladium-catalyzed asymmetric arylation of ketones.
- Ligand employed in rhodium-catalyzed 1,4-additions to enones.
- Ligand employed in palladium-catalyzed hydroamination of styrene derivatives.
- Ligand employed in silver-catalyzed asymmetric Sakuri-Hosomi allylation and Mukaiyama aldol reaction.
- Ligand employed in rhodium-catalyzed kinetic resolution of enynes.
- Ligand employed in asymmetric rhodium-catalyzed hydroboration of cyclopropenes.
- Ligand employed in silver-catalyzed a-hydroxylation of stannyl enol ethers.
- Ligand employed in palladium-catalyzed synthesis of chiral allenes.
- Ligand for palladium-catalyzed enantioselective hetero Michael addition to form b-amino acid derivatives.
- Ligand employed in rhodium-catalyzed asymmetric rearrangement of alkynyl alkenyl carbinols.
- Ligand employed in rhodium-catalyzed 1,2-addition of aluminium organyl compounds to cyclic enones.
- Ligand employed in iridium-catalyzed transfer hydrogenative allylation of benzylic alcohols.
- Ligand employed in rhodium-catalyzed asymmetric C-Si bond formation by conjugate silyl transfer using a Si-B linkage.
- Ligand employed in the iridium-catalyzed asymmetric cyclopropane-mediated carbonyl allylation of primary alcohols.
- Ligand employed in the nickel-catalyzed asymmetric α-arylation of tetralones.
- Ligand employed in the copper-catalyzed asymmetric propargylation of ketones.
- Ligand employed in the cobalt-catalyzed asymmetric reductive coupling of alkynes with alkenes.
- Ligand employed in the rhodium-catalyzed asymmetric 1,4-addition of arylalanes on trisubstituted enones.
- Ruthenium-catalyzed asymmetric hydrocyanation of imines.
- Palladium-catalyzed asymmetric intermolecular cyclization.
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