2,2'-Dithiodipyridine Chemical Properties | |
Melting point | 56-58 °C(lit.) |
density | 1.3078 (rough estimate) |
refractive index | 1.5500 (estimate) |
Fp | 210 °C |
storage temp. | 2-8°C |
solubility | methanol: soluble50mg/mL, clear to very slightly hazy, colorless to faintly brownish-yellow |
form | powder |
color | Clear colorless to yellow to tan |
Water Solubility | 5 g/L (20 ºC) |
BRN | 154629 |
CAS DataBase Reference | 2127-03-9(CAS DataBase Reference) |
NIST Chemistry Reference | Pyridine, 2,2'-dithiobis-(2127-03-9) |
Safety Information | |
Hazard Codes | Xi,Xn |
Risk Statements | 36/37/38-37-20/22 |
Safety Statements | 36/37/39-37/39-25-22-36-26 |
RIDADR | UN 3335 |
WGK Germany | 3 |
F | 10-23 |
Hazard Note | Irritant |
TSCA | Yes |
HS Code | 29333990 |
2,2'-Dithiodipyridine Usage And Synthesis | |
Chemical Properties | white to yellowish crystalline powder |
Uses | 2,2'-Dipyridyldisulfide, sometimes known as DPS, is used for preparing thiols and activating or protecting carboxylic acid with triphenylphosphine. |
Purification Methods | Recrystallise the disulfide H2O from *C6H6/pet ether (6:7), ligroin or *C6H6. The picrate has m 119o (from EtOH). [Walter et al. Justus Liebigs Ann Chem 695 7785 1966, Marckwald et al. Chem Ber 33 1556 1900, Brocklehurst & Little Biochem J 133 67,78 1973, Beilstein 21 III/IV 48.] It has been used as a 1mM solution in EtOH for the spectrophotometric estimation of thiols. Essentially the thiol displaces half the disulfide molecule liberating the 2-mercaptopyridine anion, thereby shifting the from 340nm (of the disulfide) to 268nm (of the anion) at pH 9, or 278nm in H2O. (Compare |
2,2'-Dithiodipyridine Preparation Products And Raw materials | |
Preparation Products | Finasteride |
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