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  • Product Name:   4-(Hydroxymethyl)benzoic acid
  • Synonyms:   HMBA;HMBA LINKER;4-CARBOXYBENZYL ALCOHOL;4-HYDROXYMETHYLBENZOIC ACID;RARECHEM AL BO 1443
  • CAS No.:   3006-96-0
  • Molecular Formula:   C8H8O3
  • Molecular Weight :   152.15
  • Specification :   98%
  • Place of Origin:   China
  • Appearance :   
  • Document :   Download

Description of 4-(Hydroxymethyl)benzoic acid



4-(Hydroxymethyl)benzoic acid Chemical Properties


Melting point  182-185 °C(lit.)


storage temp.  2-8°C


form  Coarse Fibers


color  White


BRN  2690023


InChIKey WWYFPDXEIFBNKE-UHFFFAOYSA-N


CAS DataBase Reference 3006-96-0(CAS DataBase Reference)




Safety Information


Hazard Codes  Xi


Risk Statements  36/37/38


Safety Statements  26-36-37/39


WGK Germany  3


HS Code  29181990




4-(Hydroxymethyl)benzoic acid Usage And Synthesis


Chemical Properties Off-white solid


Uses 4-(Hydroxymethyl)benzoic Acid is an intermediate in the synthesis of Eprosartan (E590100), a prototype of the imidazoleacrylic acid angiotensin II receptor antagonists used as an antihypertensive age nt.


Uses This linkage reagent for SPPS is essentially acid stable. It is useful in combination with Fmoc-amino acids. Its peptide esters are usually cleaved by basic or nucleophilic reagents, especially by ammonia in the preparation of peptide amides.




4-(Hydroxymethyl)benzoic acid Preparation Products And Raw materials


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