Isobutaneboronic acid Chemical Properties | |
Melting point | 108-111 °C(lit.) |
storage temp. | 0-6°C |
form | Crystalline Powder or Flakes |
color | White to cream |
CAS DataBase Reference | 84110-40-7(CAS DataBase Reference) |
Safety Information | |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 37/39-26 |
WGK Germany | 3 |
Hazard Note | Irritant |
HazardClass | IRRITANT |
Isobutaneboronic acid Usage And Synthesis | |
Description | Isobutaneboronic acid is also known as isobutylboronic acid. Isobutaneboronic acid has been used to synthesize potent and selective dipeptidyl boronic acid proteasome inhibitors, which are promising therapeutics to treat cancer and inflammatory diseases.1 |
Reference | J. Adams, M. Behnke, S. Chen, A. A. Cruickshank, L. R. Dick, L. Grenier, J. M. Klunder, Y. Ma, L. Plamondon, R. L. Stein, Potent and selective inhibitors of the proteasome: Dipeptidyl boronic acids, Bioorganic & Medicinal Chemistry Letters, 1998, vol. 8, pp. 333-338 |
Chemical Properties | white flake |
Uses | suzuki reaction |
Uses | 2-Methylpropylboronic Acid is used in the preparation of isocoumarin analogs as inhibitors of γ-secretase cleavage. Also used in the preparation of peptide boronc acid. |
Isobutaneboronic acid Preparation Products And Raw materials | |
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