Isopropenylboronic acid pinacol ester Chemical Properties | |
Melting point | 157-161 °C |
Boiling point | 47-49 °C (9 mbar) |
density | 0.894 |
refractive index | 1.4320 |
Fp | 42 °C |
storage temp. | 2-8°C |
form | Liquid |
color | Clear, colorless to brown |
InChIKey | SVSUYEJKNSMKKW-UHFFFAOYSA-N |
CAS DataBase Reference | 126726-62-3 |
Safety Information | |
Hazard Codes | Xi |
Risk Statements | 10-36/37/38-43 |
Safety Statements | 16-26-36/37 |
RIDADR | UN 1993 |
HazardClass | IRRITANT |
PackingGroup | Ⅲ |
HS Code | 29349990 |
Isopropenylboronic acid pinacol ester Usage And Synthesis | |
Description | Isopropenylboronic acid pinacol ester is a versatile ester reagent used for palladium-catalyzed Suzuki-Miyaura cross-coupling processes, inverse-electron-demand Diels-Alder reaction, Simmons-Smith cyclopropanation reaction, polyene cyclization, stereoselective aldol reactions, Grubbs cross-metathesis reaction, intramolecular Suzuki-Miyaura reaction, Stereoselective cross-metathesis, dipolar cycloaddition, iodosulfonylation, asymmetric conjugate addition and intramolecular hydroacylation and preparation of various therapeutic kinase and enzymatic inhibitors1. It can be used as an intermediate in the synthesis of variety of cyclic and acyclic organic compounds. It is also shown that the α-Substituted Allyl/Croty of this compound can be used for highly Diastereo- and Enantioselective allylboration of aldehydes2. |
Sources |
|
Uses | suzuki reaction |
Isopropenylboronic acid pinacol ester Preparation Products And Raw materials | |
Raw materials | Trimethyl borate-->Pinacol-->ISOPROPENYLMAGNESIUM BROMIDE |
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