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  • Product Name:   Isopropenylboronic acid pinacol ester
  • Synonyms:   2-Isopropenyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;2-(1-Methylethenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;2-Isopropenyl boronic acid pinacol ester;4,4,5,5-tetramethyl-2-(prop-1-en-2-yl)-1,3,2-dioxaborolane;4,4,5,5-tetramethyl-2-(1-methylethenyl)-1,3,2-dioxaborolane
  • CAS No.:   126726-62-3
  • Molecular Formula:   C9H17BO2
  • Molecular Weight :   168.04
  • Specification :   98%
  • Place of Origin:   China
  • Appearance :   
  • Document :   Download

Description of Isopropenylboronic acid pinacol ester



Isopropenylboronic acid pinacol ester Chemical Properties


Melting point  157-161 °C


Boiling point  47-49 °C (9 mbar)


density  0.894


refractive index  1.4320


Fp  42 °C


storage temp.  2-8°C


form  Liquid


color  Clear, colorless to brown


InChIKey SVSUYEJKNSMKKW-UHFFFAOYSA-N


CAS DataBase Reference 126726-62-3




Safety Information


Hazard Codes  Xi


Risk Statements  10-36/37/38-43


Safety Statements  16-26-36/37


RIDADR  UN 1993


HazardClass  IRRITANT


PackingGroup 


HS Code  29349990




Isopropenylboronic acid pinacol ester Usage And Synthesis


Description Isopropenylboronic acid pinacol ester is a versatile ester reagent used for palladium-catalyzed Suzuki-Miyaura cross-coupling processes, inverse-electron-demand Diels-Alder reaction, Simmons-Smith cyclopropanation reaction, polyene cyclization, stereoselective aldol reactions, Grubbs cross-metathesis reaction, intramolecular Suzuki-Miyaura reaction, Stereoselective cross-metathesis, dipolar cycloaddition, iodosulfonylation, asymmetric conjugate addition and intramolecular hydroacylation and preparation of various therapeutic kinase and enzymatic inhibitors1. It can be used as an intermediate in the synthesis of variety of cyclic and acyclic organic compounds. It is also shown that the α-Substituted Allyl/Croty of this compound can be used for highly Diastereo- and Enantioselective allylboration of aldehydes2.


Sources
  1. https://www.sigmaaldrich.com/catalog/product/aldrich/663212?lang=en&region=US
  2. https://www.trc-canada.com/product-detail/?I821825


Uses suzuki reaction




Isopropenylboronic acid pinacol ester Preparation Products And Raw materials


Raw materials Trimethyl borate-->Pinacol-->ISOPROPENYLMAGNESIUM BROMIDE


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