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  • Product Name:   tert-Butanesulfinamide
  • Synonyms:   2-METHYL-2-PROPANESULFINAMIDE;2-METHYL-PROPANE-2-SULFINIC ACID AMIDE;TERT-BUTYLSULPHINAMIDE;T-BUTYLSULFINAMIDE;2-METHYL-2-PROPANESULFINAMIDE, RACEMIC,&
  • CAS No.:   146374-27-8
  • Molecular Formula:   C4H11NOS
  • Molecular Weight :   121.2
  • Specification :   98%
  • Place of Origin:   China
  • Appearance :   
  • Document :   Download

Description of tert-Butanesulfinamide
tert-Butanesulfinamide Chemical Properties
Melting point  97-101 °C(lit.)
density  1.124
storage temp.  2-8°C
solubility  Soluble in methanol.
form  Powder or Crystals
color  White to tan
CAS DataBase Reference 146374-27-8(CAS DataBase Reference)
Safety Information
WGK Germany  3
tert-Butanesulfinamide Usage And Synthesis
Description (S)-tert-Butanesulfinamide (also known as 2-Methyl-2-propanesulfinamide) is used for the synthesis of 4-sulfonyliminopiperidine and its reaction with benzyl Grignard to form an important pharmaceutical building block, 4-benzyl-4-aminopiperidne.It can be also used to prepare spiro tosylaziridines via methylene insertion into the derived sulfonylimine1,2-(R)-(+)-2-Methyl-2-propanesulfinamide may be used to prepare N-(1-cyclohexylmethylidene)-2-methylpropane-2-sulfinamide via copper mediated condensation with cyclohexane carboxaldehyde. It may also be used to prepare (20E)-N-[t-butyl-(R)-sulfinyl]-3β-(t-butyldimethylsilyloxy)-pregn-5-en-20-imine, an intermediate for the development of androgen receptor antagonists. (S)-(-)-2-Methyl-2-propanesulfinamide may be used to develop benzofuran-based farnesyltransferase inhibitors as anti-cancer agents.
Chemical Properties white to light yellow crystal powde
tert-Butanesulfinamide Preparation Products And Raw materials
Preparation Products PENT-3-YN-2-AMINE

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