Home >> Product >> Heterocycle series >> 3-CHLORO-5-HYDROXY-BENZOIC ACI ...
←Return Back
  • Product Name:   3-CHLORO-5-HYDROXY-BENZOIC ACID
  • Synonyms:   5-(hydroxy)-3-chlorobenzoic acid;5-Chloro-m-salicylic Acid;3-chloro-5-hydroxy BA;Benzoic acid, 3-chloro-5-hydroxy-;GPR81 Agonist, 3Cl-5OH-BA
  • CAS No.:   53984-36-4
  • Molecular Formula:   C7H5ClO3
  • Molecular Weight :   172.57
  • Specification :   98%
  • Place of Origin:   China
  • Appearance :   
  • Document :   Download

Description of 3-CHLORO-5-HYDROXY-BENZOIC ACID
3-CHLORO-5-HYDROXY-BENZOIC ACID Chemical Properties
Melting point  244.0 to 248.0 °C
storage temp.  room temp
solubility  DMSO: soluble15mg/mL (clear solution)
color  white to beige
InChIKey RJOLIYHZZKAIET-UHFFFAOYSA-N
Safety Information
Hazard Codes  Xn
Risk Statements  22-37/38-41
Safety Statements  26-36
3-CHLORO-5-HYDROXY-BENZOIC ACID Usage And Synthesis
Uses 5-Chloro-m-salicylic Acid was studied as a potential selective lactate receptor (GPR81) agonists with antilipolytic effects.
Uses GPR81, also known as hydroxycarboxylic acid receptor 1 (HCAR1), is a recently de-orphanized receptor that is activated by lactic acid (EC50 ~ 1.5 mM) but not by other hydroxycarboxylic acids. 3-chloro-5-hydroxy Benzoic Acid (3-chloro-5-hydroxy BA) is an agonist of GPR81 (EC50 = 16 μM) that is inactive against the related GPR109a (HCAR2) receptor. It is similarly effective at GPR81 receptors from a variety of mammalian species and is bioavailable, stimulating lipolysis (increased serum free fatty acids) in mice fed high fat chow for 10 weeks. 3-chloro-5-hydroxy BA, like lactate, blocks basal ghrelin secretion by primary gastric mucosal cells.[Cayman Chemical]
3-CHLORO-5-HYDROXY-BENZOIC ACID Preparation Products And Raw materials

  Please leave your message to us :

    ( Your Information is an important part of our business,and we will not share or sell any of it to anyone.)

 
Your Name:
Email:
Product: 3-CHLORO-5-HYDROXY-BENZOIC ACID
Message:
 

3-CHLORO-5-HYDROXY-BENZOIC ACID related products :

5-NITROFLUORESCEIN |2-IODOBENZENESULFONIC ACID |Fluorescein isothiocyanate isomer I |5-Amino-3-fluorobenzonitrile |METHYL 3,5-DIBROMOBENZOATE |3,3'-Dibromo-2,2'-bithiophene |THIAZOLE, 5-(CHLOROMETHYL)-2-METHYL- |Ethyl 3-aminobenzoate |4-(CHLOROMETHYL)-2-(4-CHLOROPHENYL)-1,3-THIAZOLE |2-Chloro-3,5-bis(trifluoromethyl)aniline |4-HYDROXYAZOBENZENE-4'-SULFONIC ACID SODIUM SALT |4-Bromo-2,6-difluoroiodobenzene |2-(2-methylphenoxy)ethanamine |N-Methyl-4-nitrophenethylamine hydrochloride |2-AMINO-4-TERT-BUTYLTHIAZOLE |2-CYANO-5-FLUOROBENZYL BROMIDE |N,N-dimethyl-pyrimidine-2,5-diamine |4-Fluoro-2-methylbenzonitrile |N-[6-(Trifluoromethoxy)-2-benzothiazolyl]urea |4-CHLOROBENZOYLACETONITRILE |37(4-BROMOPHENYL)-2-THIAZOLETHIOL |5-Chloro-2-fluorobenzyl cyanide |3-Isoquinolinecarboxylic acid, 1,2-dihydro-4-hydroxy-1-oxo-, Methyl ester |5-Chloro-2-fluorobenzaldehyde |2,5-Pyrrolidinedicarboxylic acid, 1-(phenylMethyl)- |4-FLUORO-2-(TRIFLUOROMETHYL)BENZOIC ACID |4-BROMO-2-FLUOROBENZYLAMINE |2-AMINO-5-TERT-BUTYL-1,3,4-THIADIAZOLE |4-Bromo-2-methyl-6-nitroaniline |1H-Imidazole-4,5-dicarboxylic acid, 2-bromo-, 4,5-dimethyl ester |1-METHYL-1H-1,2,3-BENZOTRIAZOLE-5-CARBOXYLIC ACID |3,5-DIBROMOBENZYL ALCOHOL |5-(BROMOMETHYL)-1-METHYL-1H-1,2,3-BENZOTRIAZOLE |2,6-DIMETHYLBENZONITRILE |Isoxazole, 3-(4-fluorophenyl)- (9CI) |2-Chloro-4-trifluoromethylbenzoic acid |3-BROMO-2-METHYL-BENZOIC ACID METHYL ESTER |1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-SULFONYL CHLORIDE |2-(4-METHOXYPHENOXY)ETHYLAMINE |Diethyl 2,6-pyridinedicarboxylate |

Products

Contact Us

  • Email: info@vosunbio.com
  • Tel:+86-512-66566131,89888618
  • sales extension 8002