4-Fluoroaniline Chemical Properties | |
Melting point | -1.9 °C |
Boiling point | 187 °C767 mm Hg(lit.) |
density | 1.173 g/mL at 25 °C(lit.) |
refractive index | n |
Fp | 165 °F |
storage temp. | 2-8°C |
solubility | 33g/l |
pka | 4.65(at 25℃) |
form | Oily Liquid |
color | Clear pale yellow to red-brown |
Water Solubility | 33 g/L (20 ºC) |
Merck | 14,4169 |
BRN | 742030 |
Stability: | Stable. Incompatible with acids, oxidizing agents. |
CAS DataBase Reference | 371-40-4(CAS DataBase Reference) |
NIST Chemistry Reference | p-Fluoroaniline(371-40-4) |
EPA Substance Registry System | Benzenamine, 4-fluoro-(371-40-4) |
Safety Information | |
Hazard Codes | C,T,Xi,Xn |
Risk Statements | 22-34-36/38-33-23/24/25 |
Safety Statements | 26-36/37/39-45-37/39-28 |
RIDADR | UN 2941 6.1/PG 3 |
WGK Germany | 1 |
RTECS | BY1575000 |
Hazard Note | Toxic/Irritant |
TSCA | T |
HazardClass | 6.1 |
PackingGroup | III |
HS Code | 29214210 |
Hazardous Substances Data | 371-40-4(Hazardous Substances Data) |
4-Fluoroaniline Usage And Synthesis | |
Chemical Properties | light yellow to gold-coloured liquid |
Uses | 4-Fluoroaniline is a degradation product of Ezetimibe (E975000). 4-Fluoroaniline is used as an analytical reagent in the enzymic detection of glucose. |
Definition | ChEBI: A primary arylamine that is the derivative of aniline in which the hydrogen at position 4 has been substituted by fluorine. It is used as an intermediate in the manufacture of pharmaceuticals, herbicides and plant growth regulators. |
Uses | Intermediate in the manufacture of herbicides and plant growth regulators. |
4-Fluoroaniline Preparation Products And Raw materials | |
Preparation Products | 1-FLUORO-4-(TRIFLUOROMETHYLTHIO)BENZENE-->N-(4-(Benzyloxy)benzylidene)-4-fluoroaniline-->4-FLUORO-N-METHYLANILINE-->2-BROMO-6-METHYL-4-NITROANILINE-->6-Fluoro-4-(trifluoromethyl)quinoline-2-carboxylic acid ,97%-->4-TRIFLUOROMETHYL-QUINOLINE-2-CARBOXYLIC ACID-->Sarafloxacin-->4-(Trifluoromethyl)quinolin-2-amine-->6-Fluoro-4-(trifluoromethyl)quinolin-2-amine ,97%-->4-(Trifluoromethyl)quinoline-2-carbohydrazide ,97%-->(6-Fluoro-4-(trifluoromethyl)quinolin-2-yl)methanol ,97%-->(4-(Trifluoromethyl)quinolin-2-yl)methanol ,97%-->4-BROMO-6-FLUORO-2-(TRIFLUOROMETHYL)QUINOLINE-->Ethyl 6-fluoro-4-(trifluoromethyl)quinoline-2-carboxylate ,97%-->2-Bromo-6-fluoro-4-(trifluoromethyl)quinoline-->4-Fluorophenyl isocyanate-->2-BROMO-4-(TRIFLUOROMETHYL)QUINOLINE-->6-FLUORO-4-HYDROXY-2-(TRIFLUOROMETHYL)QUINOLINE-->2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE-->6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone |
Raw materials | Dimethyl sulfoxide-->Styrene-->4-Chloronitrobenzene-->N,N-Dimethylacetamide-->Potassium fluoride-->Poly(ethylene glycol)-->Sulfolane-->Benzotrichloride-->15-Crown-5-->4-Fluoronitrobenzene-->Fluorine-->N-Phenylhydroxylamine-->Phenyl phosphine |
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