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  • Product Name:   4-Fluoroaniline
  • Synonyms:   1,4-fluorobenzenamine;4-Fluoranilin;4-fluoranilin(czech);4-fluoro-anilin;4-fluoro-benzenamin
  • CAS No.:   371-40-4
  • Molecular Formula:   C6H6FN
  • Molecular Weight :   111.12
  • Specification :   98%
  • Place of Origin:   China
  • Appearance :   
  • Document :   Download

Description of 4-Fluoroaniline



4-Fluoroaniline Chemical Properties


Melting point  -1.9 °C


Boiling point  187 °C767 mm Hg(lit.)


density  1.173 g/mL at 25 °C(lit.)


refractive index  n20/D 1.539(lit.)


Fp  165 °F


storage temp.  2-8°C


solubility  33g/l


pka 4.65(at 25℃)


form  Oily Liquid


color  Clear pale yellow to red-brown


Water Solubility  33 g/L (20 ºC)


Merck  14,4169


BRN  742030


Stability: Stable. Incompatible with acids, oxidizing agents.


CAS DataBase Reference 371-40-4(CAS DataBase Reference)


NIST Chemistry Reference p-Fluoroaniline(371-40-4)


EPA Substance Registry System Benzenamine, 4-fluoro-(371-40-4)




Safety Information


Hazard Codes  C,T,Xi,Xn


Risk Statements  22-34-36/38-33-23/24/25


Safety Statements  26-36/37/39-45-37/39-28


RIDADR  UN 2941 6.1/PG 3


WGK Germany  1


RTECS  BY1575000


Hazard Note  Toxic/Irritant


TSCA  T


HazardClass  6.1


PackingGroup  III


HS Code  29214210


Hazardous Substances Data 371-40-4(Hazardous Substances Data)




4-Fluoroaniline Usage And Synthesis


Chemical Properties light yellow to gold-coloured liquid


Uses 4-Fluoroaniline is a degradation product of Ezetimibe (E975000). 4-Fluoroaniline is used as an analytical reagent in the enzymic detection of glucose.


Definition ChEBI: A primary arylamine that is the derivative of aniline in which the hydrogen at position 4 has been substituted by fluorine. It is used as an intermediate in the manufacture of pharmaceuticals, herbicides and plant growth regulators.


Uses Intermediate in the manufacture of herbicides and plant growth regulators.




4-Fluoroaniline Preparation Products And Raw materials


Preparation Products 1-FLUORO-4-(TRIFLUOROMETHYLTHIO)BENZENE-->N-(4-(Benzyloxy)benzylidene)-4-fluoroaniline-->4-FLUORO-N-METHYLANILINE-->2-BROMO-6-METHYL-4-NITROANILINE-->6-Fluoro-4-(trifluoromethyl)quinoline-2-carboxylic acid ,97%-->4-TRIFLUOROMETHYL-QUINOLINE-2-CARBOXYLIC ACID-->Sarafloxacin-->4-(Trifluoromethyl)quinolin-2-amine-->6-Fluoro-4-(trifluoromethyl)quinolin-2-amine ,97%-->4-(Trifluoromethyl)quinoline-2-carbohydrazide ,97%-->(6-Fluoro-4-(trifluoromethyl)quinolin-2-yl)methanol ,97%-->(4-(Trifluoromethyl)quinolin-2-yl)methanol ,97%-->4-BROMO-6-FLUORO-2-(TRIFLUOROMETHYL)QUINOLINE-->Ethyl 6-fluoro-4-(trifluoromethyl)quinoline-2-carboxylate ,97%-->2-Bromo-6-fluoro-4-(trifluoromethyl)quinoline-->4-Fluorophenyl isocyanate-->2-BROMO-4-(TRIFLUOROMETHYL)QUINOLINE-->6-FLUORO-4-HYDROXY-2-(TRIFLUOROMETHYL)QUINOLINE-->2-HYDROXY-4-(TRIFLUOROMETHYL)QUINOLINE-->6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone


Raw materials Dimethyl sulfoxide-->Styrene-->4-Chloronitrobenzene-->N,N-Dimethylacetamide-->Potassium fluoride-->Poly(ethylene glycol)-->Sulfolane-->Benzotrichloride-->15-Crown-5-->4-Fluoronitrobenzene-->Fluorine-->N-Phenylhydroxylamine-->Phenyl phosphine


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