Home >> Product >> Benzene ring series >> 4-Aminosalicylic acid
- Product Name: 4-Aminosalicylic acid
- Synonyms: 3-Hydroxy-4-carboxyaniline;4-Amino-2-hydroxbenzoicacid;4-amino-2-hydroxy-benzoicaci;4-Aminosalicyclic acid;4-aminosalicylic
- CAS No.: 65-49-6
- Molecular Formula: C7H7NO3
- Molecular Weight : 153.14
- Specification : 98%
- Place of Origin: China
- Appearance :
- Document : Download
Description of 4-Aminosalicylic acid
| 4-Aminosalicylic acid Chemical Properties | |
| Melting point | 135-145 °C(lit.) |
| Boiling point | 276.03°C (rough estimate) |
| density | 1.3585 (rough estimate) |
| refractive index | 1.5500 (estimate) |
| storage temp. | Store at 0-5°C |
| solubility | 1.69g/l |
| form | Powder |
| pka | 3.25(at 25℃) |
| color | Colorless |
| PH | 3.5 (1g/l, H2O, 20℃) |
| Water Solubility | 2 g/L (20 ºC) |
| Merck | 14,477 |
| BRN | 473071 |
| CAS DataBase Reference | 65-49-6(CAS DataBase Reference) |
| NIST Chemistry Reference | Aminosalicylic acid(65-49-6) |
| EPA Substance Registry System | Benzoic acid, 4-amino-2-hydroxy-(65-49-6) |
| Safety Information | |
| Hazard Codes | Xn,Xi,T |
| Risk Statements | 22-36-36/37/38-45-35-61 |
| Safety Statements | 26-37/39-45-53-36-36/37/39 |
| RIDADR | UN 1789 8/PG 3 |
| WGK Germany | 2 |
| RTECS | VO1225000 |
| TSCA | Yes |
| HS Code | 29225000 |
| Hazardous Substances Data | 65-49-6(Hazardous Substances Data) |
| Toxicity | LD50 orally in mice: 4 g/kg (Bavin) |
| 4-Aminosalicylic acid Usage And Synthesis | |
| Chemical Properties | beige powder |
| Uses | antimycobacterial antitubercular;NF-kB inhibitor |
| Uses | An antibiotic used to treat tuberculosis. |
| Definition | ChEBI: An aminobenzoic acid that is salicylic acid substituted by an amino group at position 4. |
| Brand name | Parasal (Panray); Paser (Jacobus). |
| Purification Methods | Crystallise the acid from EtOH. [Beilstein 14 IV 1967.] |
| 4-Aminosalicylic acid Preparation Products And Raw materials | |
| Preparation Products | optical plastics based on coplymer of diene macromolecule-->Methyl 4-acetamido-2-methoxybenzoate-->METHYL 4-ACETAMIDO-2-METHOXYBENZOATE-->4-Chlorosalicylic acid |
| Raw materials | Nitric acid-->Sodium methanolate-->CARBON DIOXIDE-->Sodium sulfite-->Sodium sulfide-->Potassium hydroxide solution-->Phenylacetic acid-->3-Aminophenol-->2-Cyanophenol-->1-Butyl nitrite-->METHYL 2,4-DINITROPHENYLACETATE-->2,4-DINITROPHENYLACETIC ACID-->4-Nitrosalicylic acid |
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