Home >> Expo Events >> Advances in the study of lethal mechanism of jellyfish toxin
ecently, the Journal of Proteomics, published by the American Chemical Society, published new progress in the field of lethal mechanism of jellyfish toxins by Li Pengcheng, a researcher at the Institute of Oceanography, Chinese Academy of Sciences. The results of this study provide theoretical guidance for the development of medicines for jellyfish stings and the emergency treatment of patients with severe jellyfish stings.

Jellyfish sting is one of the most serious public health and safety problems in the world. Every year, jellyfish stings cause a large number of injuries, disabilities and even deaths, which seriously threaten the health and safety of tourists, fishermen and soldiers in coastal areas. In recent years, there have been many jellyfish stings and deaths along the coasts of Beidaihe, Yingkou, Dalian, Weihai and Qingdao. However, at present, there are no effective drugs to treat jellyfish stings and emergencies in China, and the causes of toxic injury and death caused by jellyfish stings are not clear.

In order to reveal the mechanism of jellyfish stings and the lethal mechanism of toxins, and to develop medicines to treat jellyfish stings, Li Pengcheng's team studied jellyfish toxins in depth by using toxicological and pathological methods, proteomics technology, bioinformatics analysis and experimental verification. Toxicity and lethal mechanism of phytochemicals. The results showed that the jellyfish toxin could cause damage to blood, heart, liver and kidney. Among them, acute myocardial infarction, severe heart rate and hypotension are the most important causes of death caused by jellyfish poisoning.

Dr. Li Rongfeng, the first author of this paper, said that further studies showed that the important role of metalloproteinase toxins in the lethal process of Jellyfish Venom should not be neglected.

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