| 2,2'-Dithiodipyridine Chemical Properties | |
| Melting point | 56-58 °C(lit.) |
| density | 1.3078 (rough estimate) |
| refractive index | 1.5500 (estimate) |
| Fp | 210 °C |
| storage temp. | 2-8°C |
| solubility | methanol: soluble50mg/mL, clear to very slightly hazy, colorless to faintly brownish-yellow |
| form | powder |
| color | Clear colorless to yellow to tan |
| Water Solubility | 5 g/L (20 ºC) |
| BRN | 154629 |
| CAS DataBase Reference | 2127-03-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Pyridine, 2,2'-dithiobis-(2127-03-9) |
| Safety Information | |
| Hazard Codes | Xi,Xn |
| Risk Statements | 36/37/38-37-20/22 |
| Safety Statements | 36/37/39-37/39-25-22-36-26 |
| RIDADR | UN 3335 |
| WGK Germany | 3 |
| F | 10-23 |
| Hazard Note | Irritant |
| TSCA | Yes |
| HS Code | 29333990 |
| 2,2'-Dithiodipyridine Usage And Synthesis | |
| Chemical Properties | white to yellowish crystalline powder |
| Uses | 2,2'-Dipyridyldisulfide, sometimes known as DPS, is used for preparing thiols and activating or protecting carboxylic acid with triphenylphosphine. |
| Purification Methods | Recrystallise the disulfide H2O from *C6H6/pet ether (6:7), ligroin or *C6H6. The picrate has m 119o (from EtOH). [Walter et al. Justus Liebigs Ann Chem 695 7785 1966, Marckwald et al. Chem Ber 33 1556 1900, Brocklehurst & Little Biochem J 133 67,78 1973, Beilstein 21 III/IV 48.] It has been used as a 1mM solution in EtOH for the spectrophotometric estimation of thiols. Essentially the thiol displaces half the disulfide molecule liberating the 2-mercaptopyridine anion, thereby shifting the from 340nm (of the disulfide) to 268nm (of the anion) at pH 9, or 278nm in H2O. (Compare |
| 2,2'-Dithiodipyridine Preparation Products And Raw materials | |
| Preparation Products | Finasteride |
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