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  • Product Name:   1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde
  • Synonyms:   1-(tert-butoxycarbonyl)-4-formylpiperidine;1-BOC-4-FORMYLPIPERIDINE 95%;1-TERT-BUTOXYCARBONYLPIPERIDINE-4-CARBOXALDEHYDE;Piperidine-4-carboxaldehyde, N-BOC protected;TERT-BUTYL 4-FORMYLPIPERIDINE-1-CARBOXYLATE
  • CAS No.:   137076-22-3
  • Molecular Formula:   C11H19NO3
  • Molecular Weight :   213.27
  • Specification :   98%
  • Place of Origin:   China
  • Appearance :   
  • Document :   Download

Description of 1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde



1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde Chemical Properties


Melting point  34-40℃


Fp  >110℃


storage temp.  Hygroscopic, -20°C Freezer, Under Inert Atmosphere


solubility  Soluble in methanol.


Sensitive  Air Sensitive


InChIKey JYUQEWCJWDGCRX-UHFFFAOYSA-N


CAS DataBase Reference 137076-22-3(CAS DataBase Reference)




Safety Information


Hazard Codes  Xi,N,Xn


Risk Statements  36/37/38-50-22


Safety Statements  26-36/37/39-61


RIDADR  UN 3077 9/PG 3


HS Code  29333990




1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde Usage And Synthesis


Chemical Properties Clear Yellow Oil


Uses Reactant for synthesis of:• ;Pim-1 inhibitors1• ;Selective GPR119 agonists for type II diabetes2• ;M-tropic (R5) HIV-1 replication inhibitors3• ;HDAC inhibitors4• ;Selective 5-HT6 antagonists5Reactant for three-component vinylogous Mannich reactions6


Uses An intermediate for polycyclic indazole derivatives that are ERK inhibitors.




1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde Preparation Products And Raw materials


Raw materials Dichloromethane-->Lithium aluminium hydride-->Di-tert-butyl dicarbonate-->Sodium acetate-->Manganese dioxide-->Pyridinium chlorochromate-->Isonipecotic acid-->4-Piperidinemethanol


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