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  • Product Name:   L(-)-Pipecolinic acid
  • Synonyms:   RARECHEM BK PT F201;(S)-(-)-2-PIPERIDINECARBOXYLIC ACID;(S)-2-PIPERIDINECARBOXYLIC ACID;S-(-)-PIPECOLINIC ACID;(S)-(-)-PIPECOLIC ACID
  • CAS No.:   3105-95-1
  • Molecular Formula:   C6H11NO2
  • Molecular Weight :   129.16
  • Specification :   98%
  • Place of Origin:   China
  • Appearance :   
  • Document :   Download

Description of L(-)-Pipecolinic acid
L(-)-Pipecolinic acid Chemical Properties
Melting point  272 °C(lit.)
alpha  -27.5 º (c=5, H2O 24 ºC)
Boiling point  239.22°C (rough estimate)
density  1.1426 (rough estimate)
refractive index  -27 ° (C=4, H2O)
storage temp.  Store at RT.
pka 2.28(at 25℃)
form  Fine Crystalline Powder
color  White
Water Solubility  soluble
Merck  14,7458
BRN  81093
CAS DataBase Reference 3105-95-1(CAS DataBase Reference)
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-24/25
WGK Germany  3
L(-)-Pipecolinic acid Usage And Synthesis
Description L-Pipecolinic acid is involved in synaptic transmission in the central nervous system. It is also used as pharmaceutical intermediate. It is a lysine metabolite; defect in its catabolism is involved in hyperpipecolic acidemia, cerebro-hepato-renal syndrome, neonatal onset adrenoleukodystrophy, and infantile Refsum disease. It can be associated with some forms of epilepsy. CRYM, a taxon-specific crystallin protein that also binds thyroid hormones, is involved in the pipecolic acid pathway.
Chemical Properties white to light yellow crystal powde
Uses Pipecolic acid is involved in synaptic transmission in the central nervous system. The l-form occurs in plants.
Definition ChEBI: A pipecolate that is the conjugate acid of L--pipecolic acid.
Purification Methods It crystallises from water. The (±)-picrate has m 158-159o (from EtOH or C6H6). [Beilstein 22 H 7, 22 III/IV 97, 22/1 V 220.] The R(+)-enantiomer [1723-00-8] has m 277o(dec) and [] D 20 +27o (c 4, H2O), and the S(-)-enantiomer [3105-95-1] has m 277o(dec) and [] D 20 -26o (c 4, H2O).[cf p 603, Beilstein 22 III/IV 96, 22/1 V 220.]
L(-)-Pipecolinic acid Preparation Products And Raw materials
Preparation Products Ropivacaine

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