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  • Product Name:   4-Aminopyrimidine
  • Synonyms:   pyrimidin-4-amine analogue;3,4-Dihydro-4-iminopyrimidine;4-Pyrimidinamine;4-Pyrimidineamine;6-Aminopyrimidine
  • CAS No.:   591-54-8
  • Molecular Formula:   C4H5N3
  • Molecular Weight :   95.1
  • Specification :   98%
  • Place of Origin:   China
  • Appearance :   
  • Document :   Download

Description of 4-Aminopyrimidine



4-Aminopyrimidine Chemical Properties


Melting point  154-156 °C(lit.)


Boiling point  167.6°C (rough estimate)


density  1.1031 (rough estimate)


refractive index  1.5200 (estimate)


form  Crystals or Powder


pka 5.71(at 20℃)


color  White to slightly beige


Water Solubility  Slightly soluble in water.


λmax 273nm(EtOH)(lit.)


CAS DataBase Reference 591-54-8(CAS DataBase Reference)


NIST Chemistry Reference Pyrimidine, 4-amino-,(591-54-8)




Safety Information


Hazard Codes  Xi


Risk Statements  36/37/38


Safety Statements  26-37/39


WGK Germany  3




4-Aminopyrimidine Usage And Synthesis


Chemical Properties White to slightly beige crystals or powder


Purification Methods Recrystallise 10.6g of aminopyrimidine from hot EtOAc (200mL) to give 7.4g colourless needles as first crop; evaporation to 25mL gives a second crop of 1.7g. The hydroiodide has m 180o. The picrate has m 225o. [Brown J Soc Chem Ind (London) 69 353 1950, Beilstein 24 H 81, 24 III/IV 2130.]




4-Aminopyrimidine Preparation Products And Raw materials


Preparation Products 5-BROMOPYRIMIDIN-4-AMINE


Raw materials Sodium hydroxide-->Hydrochloric acid-->Ethyl acetate-->Diethyl ether-->Sodium sulfate-->Ammonium hydroxide-->Ammonia-->Acetonitrile-->Formaldehyde-->Potassium permanganate-->CARBON DIOXIDE-->p-Anisidine-->Palladium hydroxide-->Potassium-->Sodium cyanoborohydride-->4-Amino-2,6-dichloropyrimidine-->Pyrimidine


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