4-Aminopyrimidine Chemical Properties | |
Melting point | 154-156 °C(lit.) |
Boiling point | 167.6°C (rough estimate) |
density | 1.1031 (rough estimate) |
refractive index | 1.5200 (estimate) |
form | Crystals or Powder |
pka | 5.71(at 20℃) |
color | White to slightly beige |
Water Solubility | Slightly soluble in water. |
λmax | 273nm(EtOH)(lit.) |
CAS DataBase Reference | 591-54-8(CAS DataBase Reference) |
NIST Chemistry Reference | Pyrimidine, 4-amino-,(591-54-8) |
Safety Information | |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-37/39 |
WGK Germany | 3 |
4-Aminopyrimidine Usage And Synthesis | |
Chemical Properties | White to slightly beige crystals or powder |
Purification Methods | Recrystallise 10.6g of aminopyrimidine from hot EtOAc (200mL) to give 7.4g colourless needles as first crop; evaporation to 25mL gives a second crop of 1.7g. The hydroiodide has m 180o. The picrate has m 225o. [Brown J Soc Chem Ind (London) 69 353 1950, Beilstein 24 H 81, 24 III/IV 2130.] |
4-Aminopyrimidine Preparation Products And Raw materials | |
Preparation Products | 5-BROMOPYRIMIDIN-4-AMINE |
Raw materials | Sodium hydroxide-->Hydrochloric acid-->Ethyl acetate-->Diethyl ether-->Sodium sulfate-->Ammonium hydroxide-->Ammonia-->Acetonitrile-->Formaldehyde-->Potassium permanganate-->CARBON DIOXIDE-->p-Anisidine-->Palladium hydroxide-->Potassium-->Sodium cyanoborohydride-->4-Amino-2,6-dichloropyrimidine-->Pyrimidine |
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