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  • Product Name:   4-Piperidineethanol
  • Synonyms:   PIPERIDINEETHANOL(4-);PIPERIDIN-4-YLETHANOL;4-(2-HYDROXYETHYL)PIPERIDINE;4-HYDROXYETHYL-PIPERIDINE;4-ethanolpiperidine
  • CAS No.:   622-26-4
  • Molecular Formula:   C7H15NO
  • Molecular Weight :   129.2
  • Specification :   98%
  • Place of Origin:   China
  • Appearance :   
  • Document :   Download

Description of 4-Piperidineethanol



4-Piperidineethanol Chemical Properties


Melting point  46-47 °C(lit.)


Boiling point  131-136 °C17 mm Hg(lit.)


density  1.0059


refractive index  n20/D 1.4902(lit.)


Fp  >230 °F


CAS DataBase Reference 622-26-4(CAS DataBase Reference)


NIST Chemistry Reference 4-Ethanolpiperidine(622-26-4)


EPA Substance Registry System 4-Piperidineethanol(622-26-4)




Safety Information


Hazard Codes  Xi


Risk Statements  36/37/38


Safety Statements  26-37/39-24/25


WGK Germany  3


Hazard Note  Irritant




4-Piperidineethanol Usage And Synthesis


Chemical Properties white crystalline low melting solid


Uses Reactant for synthesis of:• ;Ursolic acid derivatives1• ;Amodiaquine analogues for treatment of cerebral malaria2• ;Spiroimidazolidinone NPC1L1 inhibitors3• ;Piperazinyl glutamate pyridines as orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation4• ;Neurokinin-2 receptor antagonists5• ;Hepatitis C virus NS5B polymerase inhibitors6


Uses 4-Piperidineethanol have been used as a intermediate in the synthetic preparation of cellular-active allosteric inhibitors of FAK




4-Piperidineethanol Preparation Products And Raw materials


Preparation Products QUINUCLIDINE HYDROCHLORIDE


Raw materials Etanol-->Diethyl ether-->Tetrahydrofuran-->Thionyl chloride-->Lithium aluminium hydride-->Sodium borohydride-->CARBON DIOXIDE-->1-Butanol-->tert-Butanol-->Sodium amide-->4-Methylpyridine-->Platinum


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