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  • Product Name:   5-(Trifluoromethyl)pyridine-2-carboxylic acid
  • Synonyms:   5-(TRIFLUOROMETHYL)PICOLINIC ACID;5-TRIFLUOROMETHYL-2-PYRIDINECARBOXYLIC ACID;5-Trifluoromethyl-2-Pyridineca;5-(Trifluoromethyl)pyridine-2-carboxylicacid97%;5-(Trifluoromethyl)picolinic acid, 2-Carboxy-5-(trifluoromethyl)pyridine
  • CAS No.:   80194-69-0
  • Molecular Formula:   C7H4F3NO2
  • Molecular Weight :   191.11
  • Specification :   98%
  • Place of Origin:   China
  • Appearance :   
  • Document :   Download

Description of 5-(Trifluoromethyl)pyridine-2-carboxylic acid



5-(Trifluoromethyl)pyridine-2-carboxylic acid Chemical Properties


Melting point  135-137°C


storage temp.  Room temperature.


form  Powder


color  Pale brown


Water Solubility  Slightly soluble in water.


CAS DataBase Reference 80194-69-0(CAS DataBase Reference)




Safety Information


Hazard Codes  Xi


Risk Statements  36/37/38


Safety Statements  26


HazardClass  IRRITANT




5-(Trifluoromethyl)pyridine-2-carboxylic acid Usage And Synthesis


Uses 5-(Trifluoromethyl)picolinic Acid is an intermediate used in the synthesis of β-secretase (BACE) inhibitors.




5-(Trifluoromethyl)pyridine-2-carboxylic acid Preparation Products And Raw materials


Raw materials Ethyl acetate-->Diethyl ether-->Tetrahydrofuran-->N,N-Dimethylformamide-->Toluene-->n-Butyllithium-->Hexane-->Nitrogen-->CARBON DIOXIDE-->Iodine-->1-Methyl-2-pyrrolidinone -->(Trifluoromethyl)trimethylsilane-->2,5-Dibromopyridine


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