CAS No:6627-53-8 5-CHLORO-2-NITROANISOLE|4-CHLORO-2-METHOXYNITROBENZENE;4-chloro-2-methoxy-1-nitro-benzen;4-Chloro-2-methoxynitrobenzene 98%;4-chloro-2-methoxy-1-nitro-benzene;4-Chloro-3-methoxy-1-nitrobenzene - Suzhou Vosun Biotech Co.,Ltd

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Product Name: 5-CHLORO-2-NITROANISOLE
Synonyms: 4-CHLORO-2-METHOXYNITROBENZENE;4-chloro-2-methoxy-1-nitro-benzen;4-Chloro-2-methoxynitrobenzene 98%;4-chloro-2-methoxy-1-nitro-benzene;4-Chloro-3-methoxy-1-nitrobenzene
CAS No.: 6627-53-8
Molecular Formula: C7H6ClNO3
Molecular Weight : 187.58
Specification : 98%
Place of Origin: China
Appearance :
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Description of 5-CHLORO-2-NITROANISOLE



5-CHLORO-2-NITROANISOLE Chemical Properties

Melting point	70-72 °C(lit.)

density	1.4219 (rough estimate)

refractive index	1.6000 (estimate)

CAS DataBase Reference	6627-53-8(CAS DataBase Reference)

EPA Substance Registry System	Benzene, 4-chloro-2-methoxy-1-nitro- (6627-53-8)



Safety Information

Hazard Codes	Xi

Risk Statements	36/37/38

Safety Statements	26-37/39-36

WGK Germany	3



5-CHLORO-2-NITROANISOLE Usage And Synthesis

Chemical Properties	SLIGHTLY YELLOW TO GREEN CRYSTALLINE POWDER

Uses	5-Chloro-2-nitroanisole is involved in the synthesis of orally bioavailable anaplastic lymphoma kinases (ALK) inhibitors as anticancer drugs. In addition it is used in the synthesis of kinesin spindle protein (KSP) inhibitors which are responsible for the spindle pole separation which occurs during mitosis in cancer cells.



5-CHLORO-2-NITROANISOLE Preparation Products And Raw materials

Raw materials	Sodium bisulfite-->Cupric sulfate-->2-Methoxy-4-nitroaniline-->2-CHLORO-5-NITROANISOLE

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