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  • Product Name:   D-DOPA
  • Synonyms:   D-3-(3,4-Dihydroxyphenyl)alanine;D-Tyrosine,3-hydroxy-;H-D-TYR(3-HYDROXY)-OH;H-D-PHE(3,4-DI-HYDROXY)-OH;D-3-HYDROXYTYROSINE
  • CAS No.:   5796-17-8
  • Molecular Formula:   C9H11NO4
  • Molecular Weight :   197.19
  • Specification :   98%
  • Place of Origin:   China
  • Appearance :   
  • Document :   Download

Description of D-DOPA



D-DOPA Chemical Properties


Melting point  276-278 °C(lit.)


alpha  D11 +13.0° (c = 5.27 in 1N HCl)


storage temp.  −20°C


solubility  0.5 M HCl: soluble


form  powder


color  white to tan


Merck  13,3454


CAS DataBase Reference 5796-17-8(CAS DataBase Reference)




Safety Information


WGK Germany  3


10-23




D-DOPA Usage And Synthesis


Chemical Properties Tan Solid


Uses A DOPA enantiomer that lacks biological activity.


Definition ChEBI: The D-enantiomer of dopa.


Purification Methods Likely impurities are vanillin, hippuric acid, 3-methoxytyrosine and 3-aminotyrosine. DOPA recrystallises from large volumes of H2O forming colourless white needles; its solubility in H2O is 0.165%, but it is insoluble in EtOH, *C6H6, CHCl3, and EtOAc. Also crystallise it by dissolving it in dilute HCl and adding dilute ammonia to give pH 5, under N2. Alternatively, crystallise it from dilute aqueous EtOH. It is rapidly oxidised in air when moist, and darkens, particularly in alkaline solution. Dry it in vacuo at 70o in the dark, and store it in a dark container preferably under N2. It has at 220.5nm (log 3.79) and 280nm (log 3.42) in 0.001N max HCl. [Yamada et al. Chem Pharm Bull Jpn 10 693 1962, Bretschneider et al. Helv Chim Acta 56 2857 1973, NMR: Jardetzky & Jardetzky J Biol Chem 233 383 1958, Beilstein 4 IV 2492, 2493.]




D-DOPA Preparation Products And Raw materials


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