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  • Product Name:   1-Methyl-4-pyrazole boronic acid pinacol ester
  • Synonyms:   1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-;1-METHYL- 4-PYRAZOLEBORONIC ACID PINACOL ESTER;1-METHYL-4-(4,4,5,5-TERAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-PYRAZOLE;1-methyl-4-(4，4，5，5-tetramethyl-1，3，2-dioxaborolan-2-yl)-1H-;1-Methyl-4-pyrazoleboronic acid pinacol ester, 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
  • CAS No.:   761446-44-0
  • Molecular Formula:   C10H17BN2O2
  • Molecular Weight :   208.07
  • Specification :   98%
  • Place of Origin:   China
  • Appearance :   
  • Document :   Download

Description of 1-Methyl-4-pyrazole boronic acid pinacol ester
1-Methyl-4-pyrazole boronic acid pinacol ester Chemical Properties
Melting point  59-64 °C(lit.)
storage temp.  Refrigerator (+4°C)
form  Crystals
color  Off-white to yellow
Water Solubility  Slightly soluble in water.
InChIKey UCNGGGYMLHAMJG-UHFFFAOYSA-N
CAS DataBase Reference 761446-44-0(CAS DataBase Reference)
Safety Information
Hazard Codes  Xn,F,Xi
Risk Statements  22-36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
Hazard Note  Irritant/Flammable
HazardClass  IRRITANT
HS Code  29349990
1-Methyl-4-pyrazole boronic acid pinacol ester Usage And Synthesis
Chemical Properties White to light yellow crystal powde
Uses Reagent used for• ;Suzuki-Miyaura cross-coupling reactions1,2,3• ;Transesterification reactions4Reagent used for preparation of• ;Aminothiazoles as γ-secretase modulators5• ;Amino-pyrido-indol-carboxamides, as potential JAK2 inhibitors for myeloproliferative disorders therapy6• ;Pyridine derivatives as TGF-β1 and activin A signalling inhibitors7• ;MK-2461 analogs as inhibitors of c-Met kinase for the treatment of cancer8
Uses suzuki reaction
1-Methyl-4-pyrazole boronic acid pinacol ester Preparation Products And Raw materials
Raw materials Tetrahydrofuran-->Potassium hydroxide -->n-Butyllithium-->Iodomethane-->Trimethyl borate-->Methyl bromide -->Pinacol-->MOLECULAR SIEVE-->4-Bromopyrazole

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