4-Aminobenzotrifluoride Chemical Properties | |
Melting point | 3-8 °C |
Boiling point | 83 °C12 mm Hg(lit.) |
density | 1.283 g/mL at 25 °C(lit.) |
refractive index | n |
Fp | 188 °F |
storage temp. | Refrigerator, Under Inert Atmosphere |
form | Liquid |
pka | 2.45(at 25℃) |
color | Clear colorless to yellow |
Water Solubility | <0.1 g/100 mL |
Sensitive | Air Sensitive |
BRN | 1564853 |
InChIKey | ODGIMMLDVSWADK-UHFFFAOYSA-N |
CAS DataBase Reference | 455-14-1(CAS DataBase Reference) |
NIST Chemistry Reference | Benzenamine, 4-(trifluoromethyl)-(455-14-1) |
EPA Substance Registry System | Benzenamine, 4-(trifluoromethyl)-(455-14-1) |
Safety Information | |
Hazard Codes | T,N,Xi,Xn |
Risk Statements | 25-36-50/53-36/37/38-33-20/21/22 |
Safety Statements | 26-45-60-61-36/37/39-36 |
RIDADR | UN 2810 6.1/PG 3 |
WGK Germany | 3 |
RTECS | XU9260000 |
Hazard Note | Toxic/Irritant |
TSCA | T |
HazardClass | 6.1 |
PackingGroup | III |
HS Code | 29214300 |
4-Aminobenzotrifluoride Usage And Synthesis | |
Chemical Properties | clear colorless to yellow liquid |
Uses | 4-Substituted aniline derivatives exert special hematotoxicity on the red blood cells and induce leukocytosis. |
Definition | ChEBI: A substituted aniline that is a benzene ring substituted with an amino group at position 1 and a trifluoromethyl group at position 4. |
4-Aminobenzotrifluoride Preparation Products And Raw materials | |
Raw materials | Hydrofluoric acid-->4-Chlorobenzaldehyde-->PHOSGENE-->Sodium bromide-->4-Nitrotoluene-->STANNOUS CHLORIDE-->p-Toluidine-->Benzotrichloride-->Phenyl isocyanate-->4-Chlorobenzotrifluoride-->FORMANILIDE-->SODIUM HYPOBROMITE-->nitrotoluene |
Preparation Products | 2-CHLORO-4-(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE-->4-TRIFLUOROMETHYL-N-METHYLANILINE 97-->Leflunomide-->ETHYL 4-HYDROXY-6-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE-->ETHYL 4-CHLORO-6-(TRIFLUOROMETHYL)-3-QUINOLINECARBOXYLATE-->2,6-BIS(TRIFLUOROMETHYL)-4-HYDROXYQUINOLINE-->4-Amino-3,5-dichlorobenzotrifluoride |
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